Calea zacatechichi has been used traditionally in Oxaca Mexico amongst the same people who use Salvia divinorum. Traditionally they have used two different methods of consumption. The first being to crush the leaves and steep in a tea. This has been said to be extremely bitter, the addition of honey has been used to improved the taste substantially. The second being to roll them into a cigarette and smoke it. Both are reported to have similar effects. The Indians claim that it clarifies the senses and induces dreams with some auditory shifting.